We are just starting to work with a partner with Cyclone and we are using Wm 4.6. Have you been successful?
Here is one tip we found:
Apparently Cyclone can’t handle a url with a “/” at the end. If you send it an EDIINT AS2 message you will get a Server Error: Service unavailable (http 503) in the Activity log for the Transaction. Taking off the / at the end of the Location setting in the Profile enabled them to receive the message.